IHC-P analysis of human liver carcinoma tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
![IHC-P analysis of human kidney tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_1445_IHC-P_w_23061419_712.webp "IHC-P analysis of human kidney tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human liver tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_1446_IHC-P_w_23061419_112.webp "IHC-P analysis of human liver tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_1447_IHC-P_w_23061419_465.webp "IHC-P analysis of human ovary tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_1448_IHC-P_w_23061419_682.webp "IHC-P analysis of human pancreas tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![WB analysis of HEK293T cells transfected with TRPM4 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83489 TRPM4 antibody [10H5]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_3665_WB_w_23061419_589.webp "WB analysis of HEK293T cells transfected with TRPM4 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83489 TRPM4 antibody [10H5]. Loading : 5 ug per lane")
![WB analysis of various cell lines using GTX83489 TRPM4 antibody [10H5]. Loading : 35 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83489/GTX83489_3666_WB_w_23061419_266.webp "WB analysis of various cell lines using GTX83489 TRPM4 antibody [10H5]. Loading : 35 ug per lane")
IHC-P analysis of human liver carcinoma tissue using GTX83489 TRPM4 antibody [10H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
TRPM4 antibody [10H5]
GTX83489
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Monkey
TargetTRPM4
Overview
- SupplierGeneTex
- Product NameTRPM4 antibody [10H5] - Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:2000. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10H5
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID54795
- Target nameTRPM4
- Target descriptiontransient receptor potential cation channel subfamily M member 4
- Target synonymscalcium-activated non-selective cation channel 1; EKVP6; hTRPM4; long transient receptor potential channel 4; LTrpC4; melastatin-4; PFHB1B; transient receptor potential cation channel subfamily M member 4; TRPM4B
- HostMouse
- IsotypeIgG1
- Protein IDQ8TD43
- Protein NameTransient receptor potential cation channel subfamily M member 4
- Scientific DescriptionCalcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload.
- ReactivityCanine, Human, Monkey
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203