Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TXNIP Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TXNIP Polyclonal Antibody at dilution 1:40
TXNIP Polyclonal Antibody
E-AB-17496
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTXNIP Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionMay act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
- UNSPSC12352203