UBE3A antibody [HL1660]

GeneTex

UBE3A antibody [HL1660]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

HL1660

1 mg/ml

Unconjugated

UBE3A

ubiquitin protein ligase E3A

ANCR, AS, E6-AP, EPVE6AP, HPVE6A, PIX1, ubiquitin-protein ligase E3A, CTCL tumor antigen se37-2, E6AP ubiquitin-protein ligase, HECT-type ubiquitin transferase E3A, human papilloma virus E6-associated protein, human papillomavirus E6-associated protein, oncogenic protein-associated protein E6-AP, renal carcinoma antigen NY-REN-54

Rabbit

IgG

Ubiquitin-protein ligase E3A

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203