
WB analysis of various sample lysates using GTX16444 UEV1A antibody. Dilution : 1:1000 Loading : 25microg per lane
UEV1A antibody
GTX16444
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUBE2V1
Overview
- SupplierGeneTex
- Product NameUEV1A antibody
- Delivery Days Customer7
- Antibody SpecificityKnockdown/Knockout validation was supported by references (PMID: 32081062)
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7335
- Target nameUBE2V1
- Target descriptionubiquitin conjugating enzyme E2 V1
- Target synonymsCIR1; CROC1; CROC-1; DNA-binding protein; TRAF6-regulated IKK activator 1 beta Uev1A; UBE2V; ubiquitin-conjugating enzyme E2 variant 1; UEV1; UEV-1; UEV1A
- HostRabbit
- IsotypeIgG
- Protein IDQ13404
- Protein NameUbiquitin-conjugating enzyme E2 variant 1
- Scientific DescriptionUbiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination.Read more