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UNC-2025

M5026
AbMole BioScience
CAS Number1429881-91-3
DownloadDatasheet
Product group Chemicals
Estimated Purity>99%
Molecular Weight476.66
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    UNC-2025
  • Delivery Days Customer
    9
  • CAS Number
    1429881-91-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C28H40N6O
  • Molecular Weight
    476.66
  • Scientific Description
    UNC2025 is a potent, ATP-competitive and highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM, respectively. UNC2025 is >45-fold selectivity for MERTK relative to Axl (IC50= 122 nM; Ki = 13.3 nM). UNC2025 exhibits an excellent PK properties.
  • SMILES
    CCCCNC1=NC=C2C(=N1)[N](C=C2C3=CC=C(CN4CCN(C)CC4)C=C3)C5CCC(O)CC5
  • UNSPSC
    12352200