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UNC2025 [1429881-91-3]

UNC2025 [1429881-91-3]

T7007
TargetMol Chemicals
CAS Number1429881-91-3
Product group Chemicals
Estimated Purity99.74%
Molecular Weight476.66
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    UNC2025 [1429881-91-3]
  • Delivery Days Customer
    4
  • CAS Number
    1429881-91-3
  • Certification
    Research Use Only
  • Chemical Name
    UNC2025
  • Estimated Purity
    99.74%
  • Molecular Formula
    C28H40N6O
  • Molecular Weight
    476.66
  • Scientific Description
    UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
  • Shelf life instruction
    3 years
  • SMILES
    CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCN(C)CC2)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Zhang W, DeRyckere D, Hunter D, et al. UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor. J Med Chem. 2014,57(16):7031-41. doi: 10.1021/jm500749d
    Read this paper

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