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ProductsBack/UNG antibody

UNG antibody

GTX103236

ApplicationsWestern Blot, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Zebra Fish

TargetUNG

Overview

Supplier
GeneTex
Product Name
UNG antibody
Delivery Days Customer
9
Applications
Western Blot, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID7374
Target name
UNG
Target description
uracil DNA glycosylase
Target synonyms
DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2, uracil-DNA glycosylase, uracil-DNA glycosylase 1, uracil-DNA glycosylase 2
Host
Rabbit
Isotype
IgG
Protein IDP13051
Protein Name
Uracil-DNA glycosylase
Scientific Description
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. [provided by RefSeq]
Reactivity
Human, Zebra Fish
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Wu D, Chen L, Sun Q, et al. Uracil-DNA glycosylase is involved in DNA demethylation and required for embryonic development in the zebrafish embryo. J Biol Chem. 2014,289(22):15463-73. doi: 10.1074/jbc.M114.561019
Read this paper
Lam T, Thomas LM, White CA, et al. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS One. 2013,8(11):e80414. doi: 10.1371/journal.pone.0080414
Read this paper

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