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UNG antibody

Research Use Only
GTX113860
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, Other Application
Product group Antibodies
ReactivityHuman
TargetUNG
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Overview

  • Supplier
    GeneTex
  • Product Name
    UNG antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.71 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7374
  • Target name
    UNG
  • Target description
    uracil DNA glycosylase
  • Target synonyms
    DGU; HIGM4; HIGM5; UDG; UNG1; UNG15; UNG2; uracil-DNA glycosylase; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP13051
  • Protein Name
    Uracil-DNA glycosylase
  • Scientific Description
    This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Repair-Assisted Damage Detection Reveals Biological Disparities in Prostate Cancer between African Americans and European Americans. Krieger KL et al., 2022 Feb 17, Cancers (Basel)
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  • A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG. Rodriguez-Barrueco R et al., 2022 Feb, Adv Sci (Weinh)
    Read more
  • DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools. Martinez-Arribas B et al., 2019 Aug 3, Cell Mol Life Sci
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  • Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway. Chou WC et al., 2015 Aug, Carcinogenesis
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