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ProductsBack/USP5 antibody [2H5]
IHC-P analysis of human colon adenocarcinoma tissue using GTX83430 USP5 antibody [2H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of human colon adenocarcinoma tissue using GTX83430 USP5 antibody [2H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of human colon adenocarcinoma tissue using GTX83430 USP5 antibody [2H5]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50

USP5 antibody [2H5]

GTX83430
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
TargetUSP5
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Overview

  • Supplier
    GeneTex
  • Product Name
    USP5 antibody [2H5] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:2000. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    2H5
  • Concentration
    0.99 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8078
  • Target name
    USP5
  • Target description
    ubiquitin specific peptidase 5
  • Target synonyms
    deubiquitinating enzyme 5; isopeptidase T; ISOT; testicular tissue protein Li 218; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin isopeptidase T; ubiquitin specific protease 5 (isopeptidase T); ubiquitin thioesterase 5; ubiquitin thiolesterase 5; ubiquitin-specific protease-5 (ubiquitin isopeptidase T); ubiquitin-specific-processing protease 5
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP45974
  • Protein Name
    Ubiquitin carboxyl-terminal hydrolase 5
  • Scientific Description
    Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored Lys-48-linked polyubiquitin disassembly. Binds linear and Lys-63-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of TP53/p53 and an increase in TP53/p53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated TP53/p53 but not with MDM2 for proteasomal recognition.
  • Reactivity
    Canine, Human, Monkey, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203