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VCAM1 / CD106 antibody [N1N2], N-term

GTX110684
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetVCAM1
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Overview

  • Supplier
    GeneTex
  • Product Name
    VCAM1 / CD106 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:20000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7412
  • Target name
    VCAM1
  • Target description
    vascular cell adhesion molecule 1
  • Target synonyms
    CD106; CD106 antigen; INCAM-100; vascular cell adhesion protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP19320
  • Protein Name
    Vascular cell adhesion protein 1
  • Scientific Description
    This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells.
    Read more
  • CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
    Read more
  • Reducing the Damage of Ox-LDL/LOX-1 Pathway to Vascular Endothelial Barrier Can Inhibit Atherosclerosis. Guo X et al., 2022, Oxid Med Cell Longev
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  • CXC chemokine ligand-13 promotes metastasis via CXCR5-dependent signaling pathway in non-small cell lung cancer. Chao CC et al., 2021 Oct, J Cell Mol Med
    Read more
  • CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Chao CC et al., 2020 Feb 17, Cancers (Basel)
    Read more
  • 1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-gamma Dependent Regulation of NF-kappaB. Linghu KG et al., 2019, Front Pharmacol
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  • Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells. Liu Y et al., 2014, PLoS One
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  • Flavanol metabolites reduce monocyte adhesion to endothelial cells through modulation of expression of genes via p38-MAPK and p65-Nf-kB pathways. Claude S et al., 2014 May, Mol Nutr Food Res
    Read more