VDAC1 antibody [N1C2]
GTX114187
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetVDAC1
Overview
- SupplierGeneTex
- Product NameVDAC1 antibody [N1C2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.46 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7416
- Target nameVDAC1
- Target descriptionvoltage dependent anion channel 1
- Target synonymsouter mitochondrial membrane protein porin 1; plasmalemmal porin; PORIN; porin 31HL; porin 31HM; sperm binding protein 1a; VDAC-1; voltage-dependent anion-selective channel protein 1
- HostRabbit
- IsotypeIgG
- Protein IDP21796
- Protein NameVoltage-dependent anion-selective channel protein 1
- Scientific DescriptionThis gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Human neurotropic polyomavirus, JC virus, agnoprotein targets mitochondrion and modulates its functions. Saxena R et al., 2021 Jan 15, VirologyRead more
- Ameliorative Effect of Sodium Selenite on Silver Nanoparticles-Induced Myocardiocyte Structural Alterations in Rats. Ma W et al., 2020, Int J NanomedicineRead more
- Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice. Silvestri E et al., 2020 Nov, FASEB JRead more
- The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells. Chang YC et al., 2020 Aug 15, Toxicol Appl PharmacolRead more
- Silver Nanoparticle Exposure Causes Pulmonary Structural Damage and Mitochondrial Dynamic Imbalance in the Rat: Protective Effects of Sodium Selenite. Ma W et al., 2020, Int J NanomedicineRead more
- Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species. Lee CW et al., 2019 Aug, J Cell PhysiolRead more
- Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway. Lin SC et al., 2018 Feb, Oncol RepRead more
- The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKbeta/AMPK pathways. Chen X et al., 2017 Aug, Redox BiolRead more
- The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. Valdez BC et al., 2017 Nov, Leuk LymphomaRead more
- Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. Eguchi A et al., 2017 Feb, HepatologyRead more