VDAC1 antibody [N1C2]
GTX114187
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetVDAC1
Overview
- SupplierGeneTex
- Product NameVDAC1 antibody [N1C2]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.46 mg/ml
- ConjugateUnconjugated
- Gene ID7416
- Target nameVDAC1
- Target descriptionvoltage dependent anion channel 1
- Target synonymsPORIN, VDAC-1, non-selective voltage-gated ion channel VDAC1, outer mitochondrial membrane protein porin 1, plasmalemmal porin, porin 31HL, porin 31HM, sperm binding protein 1a
- HostRabbit
- IsotypeIgG
- Protein IDP21796
- Protein NameNon-selective voltage-gated ion channel VDAC1
- Scientific DescriptionThis gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Saxena R, Saribas S, Jadiya P, et al. Human neurotropic polyomavirus, JC virus, agnoprotein targets mitochondrion and modulates its functions. Virology. 2021,553:135-153. doi: 10.1016/j.virol.2020.11.004Read this paper
- Ma W, He S, Xu Y, et al. Ameliorative Effect of Sodium Selenite on Silver Nanoparticles-Induced Myocardiocyte Structural Alterations in Rats. Int J Nanomedicine. 2020,15:8281-8292. doi: 10.2147/IJN.S271457Read this paper
- Silvestri E, Senese R, De Matteis R, et al. Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice. FASEB J. 2020,34(11):15146-15163. doi: 10.1096/fj.202000995RRead this paper
- Chang YC, Kondapuram SK, Yang TH, et al. The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells. Toxicol Appl Pharmacol. 2020,401:115080. doi: 10.1016/j.taap.2020.115080Read this paper
- Ma W, He S, Ma H, et al. Silver Nanoparticle Exposure Causes Pulmonary Structural Damage and Mitochondrial Dynamic Imbalance in the Rat: Protective Effects of Sodium Selenite. Int J Nanomedicine. 2020,15:633-645. doi: 10.2147/IJN.S232986Read this paper
- Lee CW, Chi MC, Chang TM, et al. Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species. J Cell Physiol. 2019,234(8):13157-13168. doi: 10.1002/jcp.27986Read this paper
- Lin SC, Chu PY, Liao WT, et al. Glycyrrhizic acid induces human MDA-MB-231 breast cancer cell death and autophagy via the ROS-mitochondrial pathway. Oncol Rep. 2018,39(2):703-710. doi: 10.3892/or.2017.6123Read this paper
- Chen X, Zhao X, Cai H, et al. The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways. Redox Biol. 2017,12:987-1003. doi: 10.1016/j.redox.2017.04.031Read this paper
- Valdez BC, Li Y, Murray D, et al. The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells. Leuk Lymphoma. 2017,58(11):2705-2716. doi: 10.1080/10428194.2017.1306647Read this paper
- Eguchi A, Lazaro RG, Wang J, et al. Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. Hepatology. 2017,65(2):475-490. doi: 10.1002/hep.28838Read this paper
Datasheet
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