VEGF Receptor 2 antibody [8A01]

GeneTex

VEGF Receptor 2 antibody [8A01] - Orthogonal Validated

9

This antibody recognizes hVEGFR-2 in western blot and immunoprecipitation assays. It shows no cross-reactivity with hVEGFR-1.

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, Other Application

Research Use Only

Monoclonal

8A01

Unconjugated

KDR

kinase insert domain receptor

CD309; fetal liver kinase-1; FLK1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; vascular endothelial growth factor receptor 2; VEGFR; VEGFR2

Mouse

IgG1

Vascular endothelial growth factor receptor 2

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203