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Vemurafenib (PLX4032)

S1267
Selleck Chemicals
CAS Number918504-65-1
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Vemurafenib (PLX4032) [918504-65-1]
  • Delivery Days Customer
    9
  • CAS Number
    918504-65-1
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    51202000