Vemurafenib (PLX4032) [918504-65-1]
S1267
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameVemurafenib (PLX4032) [918504-65-1]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionVemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
- UNSPSC12352200