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Vinexin antibody [N3C2], Internal

GTX115362
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSORBS3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Vinexin antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10174
  • Target name
    SORBS3
  • Target description
    sorbin and SH3 domain containing 3
  • Target synonyms
    SCAM-1, SCAM1, SH3D4, vinexin, sorbin and SH3 domain-containing protein 3, vinexin beta (SH3-containing adaptor molecule-1)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO60504
  • Protein Name
    Vinexin
  • Scientific Description
    The SORBS3 gene encodes 2 isoforms vinexin-alpha and -beta that are vinculin (VCL; MIM 193065)-binding cytoskeletal proteins involved in focal adhesion and cell-cell adhesion (Kioka et al., 1999 [PubMed 9885244]).[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chang YW, Huang YS. Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Cell Cycle. 2017,16(21):2046-2057. doi: 10.1080/15384101.2017.1284713
    Read this paper
  • Holle AW, McIntyre AJ, Kehe J, et al. High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Integr Biol (Camb). 2016,8(10):1049-1058.
    Read this paper
  • Chang YW, Huang YS. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS One. 2014,9(9):e107961. doi: 10.1371/journal.pone.0107961
    Read this paper