ProductsBack/Vinexin antibody [N3C2], Internal

Vinexin antibody [N3C2], Internal

Name: Vinexin antibody [N3C2], Internal
SKU: GTX115362_G10
Availability: BackOrder

GTX115362

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse

TargetSORBS3

Overview

Supplier
GeneTex
Product Name
Vinexin antibody [N3C2], Internal
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Formulation
Liquid
Gene ID10174
Target name
SORBS3
Target description
sorbin and SH3 domain containing 3
Target synonyms
SCAM1; SCAM-1; SH3D4; sorbin and SH3 domain-containing protein 3; vinexin; vinexin beta (SH3-containing adaptor molecule-1)
Host
Rabbit
Isotype
IgG
Protein IDO60504
Protein Name
Vinexin
Scientific Description
The SORBS3 gene encodes 2 isoforms vinexin-alpha and -beta that are vinculin (VCL; MIM 193065)-binding cytoskeletal proteins involved in focal adhesion and cell-cell adhesion (Kioka et al., 1999 [PubMed 9885244]).[supplied by OMIM]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Chang YW et al., 2017, Cell Cycle
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High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. Holle AW et al., 2016 Oct 10, Integr Biol (Camb)
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Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. Chang YW et al., 2014, PLoS One
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