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VPS4B antibody [N3C3]

Research Use Only
GTX115249
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetVPS4B
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Overview

  • Supplier
    GeneTex
  • Product Name
    VPS4B antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.48 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID9525
  • Target name
    VPS4B
  • Target description
    vacuolar protein sorting 4 homolog B
  • Target synonyms
    cell migration-inducing 1; cell migration-inducing gene 1 protein; MIG1; SKD1; SKD1B; suppressor of K(+) transport growth defect 1; suppressor of K+ transport defect 1; vacuolar protein sorting 4B; vacuolar protein sorting-associated protein 4B; VPS4-2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75351
  • Protein Name
    Vacuolar protein sorting-associated protein 4B
  • Scientific Description
    The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CK2 involvement in ESCRT-III complex phosphorylation. Salvi M et al., 2014 Mar 1, Arch Biochem Biophys
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