WEE1 antibody [N3C2], Internal
GTX111392
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetWEE1
Overview
- SupplierGeneTex
- Product NameWEE1 antibody [N3C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.83 mg/ml
- ConjugateUnconjugated
- Gene ID7465
- Target nameWEE1
- Target descriptionWEE1 G2 checkpoint kinase
- Target synonymsWEE1 homolog; WEE1+ homolog; WEE1A; wee1A kinase; WEE1hu; wee1-like protein kinase
- HostRabbit
- IsotypeIgG
- Protein IDP30291
- Protein NameWee1-like protein kinase
- Scientific DescriptionThis gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wee1 inhibition by MK1775 potentiates gemcitabine through accumulated replication stress leading to apoptosis in biliary tract cancer.Read more
- A unique insertion in STARD9s motor domain regulates its stability. Senese S et al., 2015 Feb 1, Mol Biol CellRead more
- Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Cheung AK et al., 2013 Aug, Mol Cancer TherRead more