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WEE1 antibody [N3C2], Internal

GTX111392
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetWEE1
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Overview

  • Supplier
    GeneTex
  • Product Name
    WEE1 antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.83 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7465
  • Target name
    WEE1
  • Target description
    WEE1 G2 checkpoint kinase
  • Target synonyms
    WEE1 homolog; WEE1+ homolog; WEE1A; wee1A kinase; WEE1hu; wee1-like protein kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP30291
  • Protein Name
    Wee1-like protein kinase
  • Scientific Description
    This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Wee1 inhibition by MK1775 potentiates gemcitabine through accumulated replication stress leading to apoptosis in biliary tract cancer.
    Read more
  • A unique insertion in STARD9s motor domain regulates its stability. Senese S et al., 2015 Feb 1, Mol Biol Cell
    Read more
  • Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma. Cheung AK et al., 2013 Aug, Mol Cancer Ther
    Read more

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