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Wnt5a antibody

Research Use Only
GTX111187
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetWNT5A
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Overview

  • Supplier
    GeneTex
  • Product Name
    Wnt5a antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.09 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7474
  • Target name
    WNT5A
  • Target description
    Wnt family member 5A
  • Target synonyms
    epididymis secretory sperm binding protein; hWNT5A; protein Wnt-5a; wingless-type MMTV integration site family, member 5A; WNT-5A protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP41221
  • Protein Name
    Protein Wnt-5a
  • Scientific Description
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload. Zou Y et al., 2021 Sep 25, Cell Death Dis
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  • Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice. Guo CH et al., 2021 Mar 29, Mar Drugs
    Read more
  • Raloxifene inhibits adipose tissue inflammation and adipogenesis through Wnt regulation in ovariectomized rats and 3 T3-L1 cells. Shen HH et al., 2019 Aug 31, J Biomed Sci
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  • Deletion of long noncoding RNA EFNA3 aggravates hypoxia-induced injury in PC-12 cells by upregulation of miR-101a. Gong W et al., 2019 Jan, J Cell Biochem
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  • Caveolin-1 down-regulation is required for Wnt5a-Frizzled 2 signalling in Ha-RasV12 -induced cell transformation. Lin HK et al., 2018 May, J Cell Mol Med
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  • Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Wang LT et al., 2017 Aug, Oncogene
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  • A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Huang T et al., 2016 Oct 4, Nat Commun
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  • Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells. Borcherding N et al., 2015 May 15, Cancer Res
    Read more