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Wnt5a antibody

Name: Wnt5a antibody
SKU: GTX111187_G10
Availability: BackOrder

GTX111187

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetWNT5A

Overview

Supplier
GeneTex
Product Name
Wnt5a antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.09 mg/ml
Conjugate
Unconjugated
Gene ID7474
Target name
WNT5A
Target description
Wnt family member 5A
Target synonyms
hWNT5A, protein Wnt-5a, WNT-5A protein, epididymis secretory sperm binding protein, wingless-type MMTV integration site family, member 5A
Host
Rabbit
Isotype
IgG
Protein IDP41221
Protein Name
Protein Wnt-5a
Scientific Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. [provided by RefSeq]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Zou Y, Pan L, Shen Y, et al. Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload. Cell Death Dis. 2021,12(10):877. doi: 10.1038/s41419-021-04152-2
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Guo CH, Hsia S, Chung CH, et al. Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice. Mar Drugs. 2021,19(4). doi: 10.3390/md19040193
Read this paper
Shen HH, Yang CY, Kung CW, et al. Raloxifene inhibits adipose tissue inflammation and adipogenesis through Wnt regulation in ovariectomized rats and 3 T3-L1 cells. J Biomed Sci. 2019,26(1):62. doi: 10.1186/s12929-019-0556-3
Read this paper
Gong W, Qie S, Huang P, et al. Deletion of long noncoding RNA EFNA3 aggravates hypoxia-induced injury in PC-12 cells by upregulation of miR-101a. J Cell Biochem. 2019,120(1):836-847. doi: 10.1002/jcb.27444
Read this paper
Lin HK, Lin HH, Chiou YW, et al. Caveolin-1 down-regulation is required for Wnt5a-Frizzled 2 signalling in Ha-Ras(V12) -induced cell transformation. J Cell Mol Med. 2018,22(5):2631-2643. doi: 10.1111/jcmm.13531
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Wang LT, Chiou SS, Chai CY, et al. Transcription factor SPZ1 promotes TWIST-mediated epithelial-mesenchymal transition and oncogenesis in human liver cancer. Oncogene. 2017,36(31):4405-4414. doi: 10.1038/onc.2017.69
Read this paper
Huang T, Alvarez AA, Pangeni RP, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016,7:12885. doi: 10.1038/ncomms12885
Read this paper
Borcherding N, Kusner D, Kolb R, et al. Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells. Cancer Res. 2015,75(10):1972-82. doi: 10.1158/0008-5472.CAN-14-2761
Read this paper

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Wnt5a antibody

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