Wogonin

AdipoGen Life Sciences

Wogonin

10

632-85-9

Research Use Only

>98%

C16H12O5

284.3

Anti-inflammatory. Increases nitric oxide (NO) production [1]. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II) [2, 5]. Antioxidant [3]. Anti-viral. Shows anti-hepatitis B virus activity [4]. MCP-1 inhibitor [6]. Shows anxiolytic effect through modulation of the GABA(A) receptor complex [7]. Antifungal [8]. Neuroprotective [9]. Anticancer compound. Apoptosis and cell cycle arrest inducer [10, 12, 14, 17, 18]. Sensitizes TNFalpha- and TRAIL-induced apoptosis [11, 12]. Antiangiogenic [13]. NF-kappaB inhibitor [15]. Telomerase activity inhibitor [16]. CDK9 inhibitor [19]. PI3K-AKT pathway modulator [20]. Autophagy inducer [21]. - Chemical. CAS: 632-85-9. Formula: C16H12O5. MW: 284.3. Isolated from Scutellaria baicalensis Georgi. Anti-inflammatory. Increases nitric oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer.

COC1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1

-20°C,2°C to 8°C

12352200