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ProductsBack/XRCC4 antibody [4H9]
IHC-P analysis of breast adenocarcinoma tissue using GTX83406 XRCC4 antibody [4H9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of breast adenocarcinoma tissue using GTX83406 XRCC4 antibody [4H9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
IHC-P analysis of breast adenocarcinoma tissue using GTX83406 XRCC4 antibody [4H9]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50

XRCC4 antibody [4H9]

GTX83406
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetXRCC4
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Overview

  • Supplier
    GeneTex
  • Product Name
    XRCC4 antibody [4H9]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:2000. IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4H9
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7518
  • Target name
    XRCC4
  • Target description
    X-ray repair cross complementing 4
  • Target synonyms
    DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ13426
  • Protein Name
    DNA repair protein XRCC4
  • Scientific Description
    Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Prensner JR et al., 2014 Mar 15, Cancer Res
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