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YAP1 antibody

GTX129151
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDeer, Human, Mouse
TargetYAP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    YAP1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.15 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10413
  • Target name
    YAP1
  • Target description
    Yes1 associated transcriptional regulator
  • Target synonyms
    65 kDa Yes-associated protein; COB1; protein yorkie homolog; transcriptional coactivator YAP1; YAP; YAP2; YAP65; Yes associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; YKI; yorkie homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP46937
  • Protein Name
    Transcriptional coactivator YAP1
  • Scientific Description
    This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction. [provided by RefSeq]
  • Reactivity
    Deer, Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts. Blokland KEC et al., 2022, Front Pharmacol
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  • PRDX2 Knockdown Inhibits Extracellular Matrix Synthesis of Chondrocytes by Inhibiting Wnt5a/YAP1/CTGF and Activating IL-6/JAK2/STAT3 Pathways in Deer Antler. Sun X et al., 2022 May 7, Int J Mol Sci
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  • A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway. Huang PY et al., 2022, Am J Cancer Res
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  • Melatonin Promotes Antler Growth by Accelerating MT1-Mediated Mesenchymal Cell Differentiation and Inhibiting VEGF-Induced Degeneration of Chondrocytes. Sun X et al., 2022 Jan 11, Int J Mol Sci
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  • HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimers disease pathology. Tanaka H et al., 2021 Oct 11, Commun Biol
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  • Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance via Inhibition of Skp2-mediated Transcriptional Addiction. Li CL et al., 2020 Oct, Anticancer Res
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  • Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment. Zhu Q et al., 2020 Feb 11, Biol Res
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  • Linc-OIP5 loss regulates migration and invasion in MDA-MB-231 breast cancer cells by inhibiting YAP1/JAG1 signaling. Zhu Q et al., 2020 Jan, Oncol Lett
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  • YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis. Pajtler KW et al., 2019 Sep 2, Nat Commun
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  • Association of nuclear localization of SHP2 and YAP1 with unfavorable prognosis in non-small cell lung cancer. Chen MJ et al., 2019 Apr, Pathol Res Pract
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