ZAK Polyclonal Antibody

Reddot Biotech

ZAK Polyclonal Antibody

5

ImmunoFluorescence, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

MAP3K20

mitogen-activated protein kinase kinase kinase 20

AZK; CNM6; HCCS-4; human cervical cancer suppressor gene 4 protein; mitogen-activated protein kinase kinase kinase 20; mitogen-activated protein kinase kinase kinase MLT; mixed lineage kinase 7; mixed lineage kinase with a leucine zipper and a sterile alpha motif; mixed lineage kinase-related kinase MRK-beta; MLK7; mlklak; MLK-like mitogen-activated protein triple kinase; MLT; MLTK; MLTKalpha; MLTKbeta; MRK; pk; SFMMP; sterile alpha motif and leucine zipper containing kinase AZK; ZAK; ZAK1 homolog, leucine zipper and sterile-alpha motif kinase

Rabbit

IgG

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Human, Mouse, Rat

-20°C

12352203