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ProductsBack/53BP1 antibody [N1], N-term

53BP1 antibody [N1], N-term

GTX102595
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetTP53BP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    53BP1 antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7158
  • Target name
    TP53BP1
  • Target description
    tumor protein p53 binding protein 1
  • Target synonyms
    53BP1, TDRD30, p202, p53BP1, TP53-binding protein 1, p53-binding protein 1, tumor protein 53-binding protein, 1, tumor suppressor p53-binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ12888
  • Protein Name
    TP53-binding protein 1
  • Scientific Description
    May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Uyeda A, Onishi K, Hirayama T, et al. Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. J Neurosci. 2020,40(47):9012-9027. doi: 10.1523/JNEUROSCI.0319-20.2020
    Read this paper
  • Onishi K, Uyeda A, Shida M, et al. Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development. J Neurosci. 2017,37(35):8444-8458. doi: 10.1523/JNEUROSCI.0665-17.2017
    Read this paper
  • Chang HY, Shih MH, Huang HC, et al. Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells. PLoS One. 2013,8(1):e54117. doi: 10.1371/journal.pone.0054117
    Read this paper

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