ProductsBack/53BP1 antibody [N1], N-term

53BP1 antibody [N1], N-term

Name: 53BP1 antibody [N1], N-term
SKU: GTX102595_G10
Availability: BackOrder

GTX102595

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse

TargetTP53BP1

Overview

Supplier
GeneTex
Product Name
53BP1 antibody [N1], N-term
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID7158
Target name
TP53BP1
Target description
tumor protein p53 binding protein 1
Target synonyms
53BP1, TDRD30, p202, p53BP1, TP53-binding protein 1, p53-binding protein 1, tumor protein 53-binding protein, 1, tumor suppressor p53-binding protein 1
Host
Rabbit
Isotype
IgG
Protein IDQ12888
Protein Name
TP53-binding protein 1
Scientific Description
May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Uyeda A, Onishi K, Hirayama T, et al. Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. J Neurosci. 2020,40(47):9012-9027. doi: 10.1523/JNEUROSCI.0319-20.2020
Read this paper
Onishi K, Uyeda A, Shida M, et al. Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development. J Neurosci. 2017,37(35):8444-8458. doi: 10.1523/JNEUROSCI.0665-17.2017
Read this paper
Chang HY, Shih MH, Huang HC, et al. Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells. PLoS One. 2013,8(1):e54117. doi: 10.1371/journal.pone.0054117
Read this paper