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53BP1 antibody [N1], N-term

GTX102595
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetTP53BP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    53BP1 antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7158
  • Target name
    TP53BP1
  • Target description
    tumor protein p53 binding protein 1
  • Target synonyms
    53BP1; p202; p53-binding protein 1; p53BP1; TDRD30; TP53-binding protein 1; tumor protein 53-binding protein, 1; tumor suppressor p53-binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ12888
  • Protein Name
    TP53-binding protein 1
  • Scientific Description
    May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Suppression of DNA Double-Strand Break Formation by DNA Polymerase beta in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. Uyeda A et al., 2020 Nov 18, J Neurosci
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  • Genome Stability by DNA Polymerase beta in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development. Onishi K et al., 2017 Aug 30, J Neurosci
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  • Middle infrared radiation induces G2/M cell cycle arrest in A549 lung cancer cells. Chang HY et al., 2013, PLoS One
    Read more