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ABL1 antibody

Research Use Only
ORB66952
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetABL1
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Overview

  • Supplier
    Biorbyt
  • Product Name
    ABL1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID25
  • Target name
    ABL1
  • Target description
    ABL proto-oncogene 1, non-receptor tyrosine kinase
  • Target synonyms
    Abelson tyrosine-protein kinase 1; ABL; ABL protooncogene 1 nonreceptor tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; BCR-ABL; c-ABL; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; CHDSKM; JTK7; p150; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; truncated ABL protooncogene 1 nonreceptor tyrosine kinase; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia viral oncogene homolog 1
  • Host
    Rabbit
  • Protein IDP00519
  • Protein Name
    Tyrosine-protein kinase ABL1
  • Scientific Description
    Rabbit polyclonal to ABL1.The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has beenimplicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activityof ABL1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turnsABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR(MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNAbindingactivity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediatedphosphorylation, suggesting a cell cycle function for ABL1 (provided by RefSeq).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203