ADAMTS5 antibody

GeneTex

ADAMTS5 antibody

9

This antibody is specific for ADAMTS5 and shows no cross-reactivity with other ADAMTS family members.

WB: 1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif 5

a disintegrin and metalloproteinase with thrombospondin motifs 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); ADAM-TS 11; ADAM-TS 5; ADAMTS11; ADAMTS-11; ADAM-TS5; ADAMTS-5; ADMP-2; aggrecanase-2

Rabbit

IgG

A disintegrin and metalloproteinase with thrombospondin motifs 5

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]

Bovine, Human, Mouse, Porcine

-20°C or -80°C,2°C to 8°C

12352203