
Western blot analysis on (A) C2C12, (B) PC-12, (C) HeLa, and (D) HepG2 cell lysates using anti-Type-1 Angiotensin II receptor RabMAb (cat. #GTX63229).
AGTR1 antibody [EPR3873]
GTX63229
Overview
- SupplierGeneTex
- Product NameAGTR1 antibody [EPR3873]
- Delivery Days Customer9
- Application Supplier NoteRecommended Starting Dilutions:For WB: Use at 1:1,000 - 10,000Not yet tested in other applications. Optimal dilutions should be determined experimentally by the researcher.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEPR3873
- ConjugateUnconjugated
- Gene ID185
- Target nameAGTR1
- Target descriptionangiotensin II receptor type 1
- Target synonymsAG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R; type-1 angiotensin II receptor; type-1B angiotensin II receptor
- HostRabbit
- IsotypeIgG
- Protein IDP30556
- Protein NameType-1 angiotensin II receptor
- Scientific DescriptionAngiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Losartan treatment attenuates hindlimb unloading-induced atrophy in the soleus muscle of female rats via canonical TGF-beta signaling.Read more