Bio-Connect

AKT1 Antibody

Research Use Only
ORB639633
Biorbyt
ApplicationsImmunoHistoChemistry
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    AKT1 Antibody
  • Delivery Days Customer
    16
  • Applications
    ImmunoHistoChemistry
  • Applications Supplier
    Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml IHC-P, WB
  • Certification
    Research Use Only
  • Clone ID
    AKT1/2784
  • Isotype
    IgG
  • Scientific Description
    Recognizes a protein of 62kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.
  • UNSPSC
    12352203