alpha Cardiac Muscle Actin antibody
GTX101876
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetACTC1
Overview
- SupplierGeneTex
- Product Namealpha Cardiac Muscle Actin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.39 mg/ml
- ConjugateUnconjugated
- Gene ID70
- Target nameACTC1
- Target descriptionactin alpha cardiac muscle 1
- Target synonymsACTC; actin, alpha cardiac muscle 1; ASD5; CMD1R; CMH11; LVNC4
- HostRabbit
- IsotypeIgG
- Protein IDP68032
- Protein NameActin, alpha cardiac muscle 1
- Scientific DescriptionActins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Actin Alpha 2, Smooth Muscle (ACTA2) Is Involved in the Migratory Potential of Malignant Gliomas, and Its Increased Expression at Recurrence Is a Significant Adverse Prognostic Factor.Read more
- Cardiomyogenic Differentiation Potential of Human Dilated Myocardium-Derived Mesenchymal Stem/Stromal Cells: The Impact of HDAC Inhibitor SAHA and Biomimetic Matrices. Miksiunas R et al., 2021 Nov 24, Int J Mol SciRead more
- RYBP is important for cardiac progenitor cell development and sarcomere formation. Henry S et al., 2020, PLoS OneRead more
- Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells. Miksiunas R et al., 2020 Jul 8, Int J Mol SciRead more
- Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential. Oldershaw R et al., 2019 May 1, Stem Cells DevRead more
- Actin, alpha, cardiac muscle 1 (ACTC1) knockdown inhibits the migration of glioblastoma cells in vitro. Wanibuchi M et al., 2018 Sep 15, J Neurol SciRead more
- The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide. Unuma K et al., 2018 Jan 8, Biochem Biophys Res CommunRead more
- Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells. Robertson SYT et al., 2017, Front PhysiolRead more