alpha Smooth Muscle Actin antibody
GTX100034
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACTA2
Overview
- SupplierGeneTex
- Product Namealpha Smooth Muscle Actin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.79 mg/ml
- ConjugateUnconjugated
- Gene ID59
- Target nameACTA2
- Target descriptionactin alpha 2, smooth muscle
- Target synonymsACTSA, SMDYS, actin, aortic smooth muscle, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, cell growth-inhibiting gene 46 protein
- HostRabbit
- IsotypeIgG
- Protein IDP62736
- Protein NameActin, aortic smooth muscle
- Scientific DescriptionThe protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Kunitatsu K, Yamamoto Y, Nasu S, et al. Novel Peritoneal Sclerosis Rat Model Developed by Administration of Bleomycin and Lansoprazole. Int J Mol Sci. 2023,24(22). doi: 10.3390/ijms242216108Read this paper
- Son B, Kim M, Won H, et al. Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration. J Nanobiotechnology. 2023,21(1):310. doi: 10.1186/s12951-023-02053-4Read this paper
- García-Arroyo FE, Gonzaga-Sánchez G, Silva-Palacios A, et al. Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK). Antioxidants (Basel). 2023,12(5). doi: 10.3390/antiox12051023Read this paper
- Conroy LR, Clarke HA, Allison DB, et al. Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis. Nat Commun. 2023,14(1):2759. doi: 10.1038/s41467-023-38437-1Read this paper
- Chiou WC, Huang GJ, Chang TY, et al. Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway. Biomed Pharmacother. 2023,161:114481. doi: 10.1016/j.biopha.2023.114481Read this paper
- Fuentes-Mateos R, Santos E, Fernández-Medarde A. Optimized Protocol for Isolation and Culture of Murine Neonatal Primary Lung Fibroblasts. Methods Protoc. 2023,6(1). doi: 10.3390/mps6010014Read this paper
- Andreucci E, Bugatti K, Peppicelli S, et al. Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer. Int J Mol Sci. 2023,24(2). doi: 10.3390/ijms24021475Read this paper
- Chi JY, Hsiao YW, Liang HY, et al. Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosis. Clin Transl Med. 2022,12(11):e1099. doi: 10.1002/ctm2.1099Read this paper
- Yang AM, Lin CY, Liu SH, et al. Saccharomyces Boulardii Ameliorates Non-alcoholic Steatohepatitis in Mice Induced by a Methionine-Choline-Deficient Diet Through Gut-Liver Axis. Front Microbiol. 2022,13:887728. doi: 10.3389/fmicb.2022.887728Read this paper
Datasheet
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