Anti-Alpha Actinin 4 [Ab01AA4]

Absolute Antibody

Anti-Alpha Actinin 4 [Ab01AA4]

7

This antibody specific for an ALPHA-ACTININ-4 antigen, including the heavy chain CDR antigen binding site amino acid sequences CDR1, CDR2, and CDR3.

A protein obtained using this antibody is digested with trypsin and analyzed by MALDI-MS. From the analysis it was determined that this protein was alpha-actinin-4 (US9040018). An 8% Tris-glycine gel shows recombinant alpha-actinin-4 protein, and soluble alpha-actinin-4 protein from KATO-3 conditioned cell medium isolated with this antibody (US9040018). ELISA was performed using this antibody on plasma samples (Control: plasma from healthy people, Breast Cancer: plasma from breast cancer patients) from control and patient groups (US9040018). Immunohistochemistry is performed with this antibody using a Actinin-4 IHC Kit on a total of 714 breast tumor and control samples (US9040018).

ImmunoPrecipitation, ELISA, ImmunoHistoChemistry

ELISA; IHC; IP

Research Use Only

Monoclonal

Ab01AA4

ACTN4

actinin alpha 4

ACTININ-4; alpha-actinin-4; focal segmental glomerulosclerosis 1; FSGS; FSGS1; non-muscle alpha-actinin 4

Human

IgG1

Alpha-actinin-4

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2 format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

The original antibody was raised by immunizing mice with human breast cancer cell line SKBR3.

-20°C,2°C to 8°C

12352203