anti-CDC25B phospho (Ser149) antibody
ARG51837
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetCdc25b
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CDC25B phospho (Ser149) antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID12531
- Target nameCdc25b
- Target descriptioncell division cycle 25B
- Target synonymsAI604853; dual specificity phosphatase Cdc25B; M-phase inducer phosphatase 2
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionCdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
- ReactivityMouse
- Storage Instruction-20°C
- UNSPSC12352203