Anti-CTGF [HL2198]

Absolute Antibody

Anti-CTGF [HL2198]

9

This antibody binds aa 81-94 of hCTGF corresponding to the 2nd domain (Von Willebrand Factor - Type C Repeat). CTGF is a cysteine-rich, matrix-associated, heparin-binding protein. It corss-reacts with similar proteins form the CCN family, such as hCYR1 an

Proteolytically generated fragments of CTGF that retain functionality have been measured in biological fluids; this monoclonal antibody was designed with the intention to: a) discern between cleaved and uncleaved forms on the basis of a loss of immunoreactivity after cleavage (i.e. aa 187-197). This clone bindsaa 81-94 of hCTGF corresponding to the 2nd domain (Von Willebrand Factor - Type C Repeat). b) Develop a sandwich ELISA using two mAbs per fragment, where one mAb is the capture antibody and the other is the detector (together with our non-competitive clones Ab02551 (HL2180) and Ab02552 (HL2181) which recognize distinct regions of CTGF.

ELISA

Research Use Only

Monoclonal

HL2198

CCN2

cellular communication network factor 2

CCN family member 2; connective tissue growth factor; CTGF; HCS24; hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; insulin-like growth factor-binding protein 8; NOV2

Human

IgG1

Connective tissue growth factor

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2c format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203