CTGF antibody
GTX124232
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCCN2
Overview
- SupplierGeneTex
- Product NameCTGF antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.42 mg/ml
- ConjugateUnconjugated
- Gene ID1490
- Target nameCCN2
- Target descriptioncellular communication network factor 2
- Target synonymsCTGF, HCS24, IBP-8, IGFBP8, KMD, NOV2, SEMDLSL, CCN family member 2, IGF-binding protein 8, connective tissue growth factor, hypertrophic chondrocyte-specific protein 24, insulin-like growth factor-binding protein 8
- HostRabbit
- IsotypeIgG
- Protein IDP29279
- Protein NameCCN family member 2
- Scientific DescriptionThe protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Schneider M, Pawlak R, Weber GR, et al. A novel ocular function for decorin in the aqueous humor outflow. Matrix Biol. 2021,97:1-19. doi: 10.1016/j.matbio.2021.02.002Read this paper
- Arellano-Buendía AS, Castañeda-Lara LG, Loredo-Mendoza ML, et al. Effects of Allicin on Pathophysiological Mechanisms during the Progression of Nephropathy Associated to Diabetes. Antioxidants (Basel). 2020,9(11). doi: 10.3390/antiox9111134Read this paper
- Huang S, Cao Y, Guo H, et al. Up-regulated acylglycerol kinase (AGK) expression associates with gastric cancer progression through the formation of a novel YAP1-AGK-positive loop. J Cell Mol Med. 2020,24(19):11133-11145. doi: 10.1111/jcmm.15613Read this paper
- Miyazaki N, Katsura R, Hamada K, et al. Blueberry Prevents the Bladder Dysfunction in Bladder Outlet Obstruction Rats by Attenuating Oxidative Stress and Suppressing Bladder Remodeling. Nutrients. 2020,12(5). doi: 10.3390/nu12051285Read this paper
- Zhu L, Huang S, Li J, et al. Sophoridine inhibits lung cancer cell growth and enhances cisplatin sensitivity through activation of the p53 and Hippo signaling pathways. Gene. 2020,742:144556. doi: 10.1016/j.gene.2020.144556Read this paper
- Mohankumar K, Li X, Sung N, et al. Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis. Endocrinology. 2020,161(4). doi: 10.1210/endocr/bqaa027Read this paper
- Noe N, Shim A, Millette K, et al. Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia. Lab Invest. 2019,99(9):1363-1375. doi: 10.1038/s41374-019-0256-3Read this paper
- Nakai K, Karita S, Igarashi J, et al. COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis. J Dermatol Sci. 2019,94(1):205-212. doi: 10.1016/j.jdermsci.2019.02.003Read this paper
- Canaud G, Brooks CR, Kishi S, et al. Cyclin G1 and TASCC regulate kidney epithelial cell G(2)-M arrest and fibrotic maladaptive repair. Sci Transl Med. 2019,11(476). doi: 10.1126/scitranslmed.aav4754Read this paper
- Gao L, Gao R, Mao W, et al. PTGFR activation promotes the expression of PTGS-2 and growth factors via activation of the PKC signaling pathway in bovine endometrial epithelial cells. Anim Reprod Sci. 2018,199:30-39. doi: 10.1016/j.anireprosci.2018.10.003Read this paper
Datasheet
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