Anti-ERG Antibody

HUABIO

Anti-ERG Antibody

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ERG

ETS transcription factor ERG

LMPHM14, erg-3, p55, transcriptional regulator ERG, ERG, ETS transcription factor, FUS/ERG fusion protein, TMPRSS2/ERG fusion, ets-related, transcriptional regulator ERG (transforming protein ERG), v-ets avian erythroblastosis virus E26 oncogene homolog, v-ets avian erythroblastosis virus E26 oncogene related, v-ets erythroblastosis virus E26 oncogene homolog, v-ets erythroblastosis virus E26 oncogene like

Rabbit

IgG

Transcriptional regulator ERG

Transcriptional regulator ERG is a nuclear protein that binds purine-rich sequences of DNA. Transcriptional regulator ERG is required for platelet adhesion to the subendothelium and regulates hematopoiesis. It has a DNA binding domain and a PNT (pointed) domain. ERG is expressed at higher levels in early myelocytes than in mature lymphocytes (types of white blood cells). Therefore ERG may act as a regulator of differentiation of early hematopoietic cells. This gene can be classified as a proto-oncogene, which participates in chromosomal translocations (a popular example of this phenomenon is the Philadelphia chromosome). Essentially during cell division ERG can accidentally get stuck onto a different chromosome than where it belongs.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161