Anti-Integrin alpha-1 [AQC2], Human IgG1, kappa

Absolute Antibody

Anti-Integrin alpha-1 [AQC2], Human IgG1, kappa

9

This antibody is specific for VLA-1

The structure of the humanized version of this antibody was determined using x-ray crystallography. The humanized antibody was used for an ELISA on human alpha 1 beta 1 I domain (Karpusas et al., 2003; PMID:12662928). This antibody was used for a western blot on alpha-1 integrin of different animals, showing that this antibody could also bind sheep alpha-1 integrin. This antibody was used as an aerosol to prevent allergic reactions in the lungs of sheep. It only showed an effect on the late airway responses and no effect on the initial allergic reaction (Abraham et al., 2004; PMID:14578216).

Western Blot, ELISA, Other Application

Research Use Only

Monoclonal

AQC2

ITGA1

integrin subunit alpha 1

CD49 antigen-like family member A; CD49a; integrin alpha-1; laminin and collagen receptor; very late activation protein 1; very late antigen-1; VLA1; VLA-1

Human

IgG1

Integrin alpha-1

Human, Sheep

-20°C,2°C to 8°C

12352203