Anti-Mesothelin [MOR06626]

Absolute Antibody

Anti-Mesothelin [MOR06626]

9

This antibody binds the human and murine mesothelin. Mesothelin is a differentiation antigen present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. Because of its li

The binding reactivity of the Fab version of this antibody towards human and murine mesothelin was done using ELISA. The Fab version of this antibody binds human and murine meosthelin with a binding affinity of Kd= 6.7 x 10-10 and Kd= 6.7 x 10-9 (US9023351). The IgG1 version of this antibody was used to detect mesothelin on NCI-H226 cells by flow cytometry (US9023351).

Flow Cytometry, ELISA

Research Use Only

Monoclonal

MOR06626

MSLN

mesothelin

CAK1 antigen; megakaryocyte potentiating factor; mesothelin; MPF; pre-pro-megakaryocyte-potentiating factor; SMRP; soluble MPF mesothelin related protein

Rabbit

IgG

Mesothelin

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse

-20°C,2°C to 8°C

12352203