Anti-NKp46 [Bab281]

Absolute Antibody

Anti-NKp46 [Bab281]

9

The antibody is specific for human NKp46. The antibody cross-reacts with macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells.

The antibody was used to immunoprecipitate NKp46 molecules from NK and COS-7 cells (Pessino et al., 1998; PMID 9730896 and Cantoni et al. 1999; PMID: 10049942). NK cells were analyzed for NKp46 surface expression by immunofluorescence and Flow Cytometry analysis using the antibody (Sivori et al., 1999; PMID: 10359120). The antibody binding to NKp46 promoted an increase of cytolytic activity in NK cells (Sivori et al., 1997; PMID: 9314561 and Sivori et al., 1999; PMID: 10359120).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation

Research Use Only

Monoclonal

Bab281

NCR1

natural cytotoxicity triggering receptor 1

CD335; LY94; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; natural killer cell p46-related protein; NK cell-activating receptor; NKP46; NK-p46

Mouse

IgG1

Natural cytotoxicity triggering receptor 1

Human, Primate

-20°C,2°C to 8°C

12352203