Anti-PAI-1 [8H9D4]
Ab03641-1.1
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
TargetSERPINE1
Overview
- SupplierAbsolute Antibody
- Product NameAnti-PAI-1 [8H9D4]
- Delivery Days Customer7
- Application Supplier NoteThis antibody is reported to have strong inhibitory effect towards PAI-1 activity. The cross reactivity of this antibody towards other PAI-1 than human was done using ELISA (PMID: 9048903). This antibody shifts the reaction to the substrate pathway without decreasing the rate-limiting constant for reactive center loop insertion by tPA (PMID: 12223472). This antibody interferes with the final locking step in the serpin/proteinase interaction, thereby explaining its substrate inducing properties (PMID: 12871373).
- ApplicationsELISA, Neutralisation/Blocking
- Applications SupplierInhibit; neutralize; ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID8H9D4
- Gene ID5054
- Target nameSERPINE1
- Target descriptionserpin family E member 1
- Target synonymsendothelial plasminogen activator inhibitor; PAI; PAI1; PAI-1; PLANH1; plasminogen activator inhibitor 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serpin E1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- HostMouse
- IsotypeIgG1
- Protein IDP05121
- Protein NamePlasminogen activator inhibitor 1
- Reactivity SupplierHuman, pig
- Reactivity Supplier NoteThe original antibody was generated using PAI-1 complex as an immunogen.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
![WB analysis of HepG2 whole cell lysate using GTX02817 PAI-1 antibody [GT1223]. Dilution : 1:1000 Loading : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX02817/CutImage_A19096_WB_01_(1069081)_w_23053122_189.webp)





