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Anti-PAI-1 [8H9D4]

Ab03641-1.1
Absolute Antibody
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
TargetSERPINE1
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-PAI-1 [8H9D4]
  • Delivery Days Customer
    7
  • Application Supplier Note
    This antibody is reported to have strong inhibitory effect towards PAI-1 activity. The cross reactivity of this antibody towards other PAI-1 than human was done using ELISA (PMID: 9048903). This antibody shifts the reaction to the substrate pathway without decreasing the rate-limiting constant for reactive center loop insertion by tPA (PMID: 12223472). This antibody interferes with the final locking step in the serpin/proteinase interaction, thereby explaining its substrate inducing properties (PMID: 12871373).
  • Applications
    ELISA, Neutralisation/Blocking
  • Applications Supplier
    Inhibit; neutralize; ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    8H9D4
  • Gene ID5054
  • Target name
    SERPINE1
  • Target description
    serpin family E member 1
  • Target synonyms
    endothelial plasminogen activator inhibitor; PAI; PAI1; PAI-1; PLANH1; plasminogen activator inhibitor 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serpin E1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP05121
  • Protein Name
    Plasminogen activator inhibitor 1
  • Reactivity Supplier
    Human, pig
  • Reactivity Supplier Note
    The original antibody was generated using PAI-1 complex as an immunogen.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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