IgD (human) Matched Antibody Pair

Catalog number: REV-31-1025-MK-KI01
Brand: RevMAb Biosciences
Packing: 1 set
Price: € 660.00
Expected delivery time: 7 days
Sandwich ELISA using RM123 as the c...

Product specifications for - IgD (human) Matched Antibody Pair

Product group: Antibodies
Category: Antibody pairs, sets and duos
Application: ELISA
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: -20-¦C
Scientific information: 
Scientific info: The Human IgD Matched Antibody Pairs is specific to Human IgD and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data. Immunoglobulin D (IgD) is an antibody isotype that makes up about 1% of proteins in the plasma membranes of immature B-lymphocytes where it is usually co-expressed with IgM. IgD is also produced in a secreted form that is found in very small amounts in blood serum, representing 0.25% of immunoglobulins in serum. Secreted IgD is produced as a monomeric antibody with two heavy chains of the delta (delta) class, and two Ig light chains. In B cells, the function of IgD is to signal the B cells to be activated. By being activated, B cells are ready to take part in the defense of the body as part of the immune system. IgD was found to bind to basophils and mast cells and activate these cells to produce antimicrobial factors to participate in respiratory immune defense in humans. It also stimulates basophils to release B cell homeostatic factors.
Swiss prot ID: P01880
Safety information: 
Hazard information: Non-hazardous
Additional information: 
Synonyms: Ig delta chain C region; Ig delta chain C region NIG-65; Ig delta chain C region WAH