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Sandwich ELISA using RM122 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.
Sandwich ELISA using RM122 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.
Sandwich ELISA using RM122 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.

IgE (human) Matched Antibody Pair

Research Use Only
REV-31-1024-MK
RevMAb Biosciences
ApplicationsELISA
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    IgE (human) Matched Antibody Pair
  • Delivery Days Customer
    5
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Scientific Description
    The Human IgE Matched Antibody Pairs is specific to Human IgE and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data. Immunoglobulin E (IgE) is an antibody isotype that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains (Cepsilon1-Cepsilon4). IgEs main function is immunity to parasites such as helminths or certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a last line of defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings and antigen preparations used in desensitization immunotherapy. - The Human IgE Matched Antibody Pairs is specific to Human IgE and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin E (IgE) is an antibody isotype that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains (Cepsilon1-Cepsilon4). IgEs main function is immunity to parasites such as helminths or certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a last line of defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic reactions to drugs, bee stings and antigen preparations used in desensitization immunotherapy.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203