APC Anti-Mouse IL-17A Antibody

Reddot Biotech

APC Anti-Mouse IL-17A Antibody

5

Flow Cytometry, ImmunoCytoChemistry

Research Use Only

Monoclonal

TC11-18H10.1

APC (Allophycocyanin)

Il17a

interleukin 17A

Ctla-8, Ctla8, IL-17, IL-17A, Il17, interleukin-17A, cytotoxic T-lymphocyte-associated antigen 8

Rat

IgG1

Interleukin-17A

IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-kappaB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course. - This is a APC Anti-Mouse IL-17A Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Mouse

2°C to 8°C

41116161