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Chemical Structure

Apigenin 7-glucoside

CDX-A0568
Chemodex
CAS Number578-74-5
Product group Chemicals
Estimated Purity>97%
Molecular Weight432.38
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Overview

  • Supplier
    Chemodex
  • Product Name
    Apigenin 7-glucoside [578-74-5]
  • Delivery Days Customer
    10
  • CAS Number
    578-74-5
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Molecular Formula
    C21H20O10
  • Molecular Weight
    432.38
  • Scientific Description
    Apigenin 7-glucoside is a flavonoid with anti-inflammatory, antioxidant, anticancer, anti-adipogenic and anxiolytic activities. It has been shown to inhibit LPS-induced nitric oxide production in RAW 264.7 cells or have hepatoprotective activity due to its antioxidant activities, acting as scavengers of ROS. Apigenin 7-glucoside has been shown to have anti-proliferative activity, possible through cell cycle inhibition and consequently induce apoptosis. it also has the ability to enhance melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells. Apigenin 7-glucoside has shown neuroprotective effects possibly by inhibiting neuroinflammation and its antioxidant activity. Apigenin-7-O-glucoside inhibits adipogenesis of 3T3-L1 preadipocytes at early stage of adipogenesis at high concentrations, by downregulating PPARgamma and CEBP-alpha. - Chemical. CAS: 578-74-5. Formula: C21H20O10. MW: 432.38. Apigenin 7-glucoside is a flavonoid with anti-inflammatory, antioxidant, anticancer, anti-adipogenic and anxiolytic activities. It has been shown to inhibit LPS-induced nitric oxide production in RAW 264.7 cells or have hepatoprotective activity due to its antioxidant activities, acting as scavengers of ROS. Apigenin 7-glucoside has been shown to have anti-proliferative activity, possible through cell cycle inhibition and consequently induce apoptosis. it also has the ability to enhance melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells. Apigenin 7-glucoside has shown neuroprotective effects possibly by inhibiting neuroinflammation and its antioxidant activity. Apigenin-7-O-glucoside inhibits adipogenesis of 3T3-L1 preadipocytes at early stage of adipogenesis at high concentrations, by downregulating PPARgamma and CEBP-alpha.
  • SMILES
    O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC(OC(C3=CC=C(O)C=C3)=CC4=O)=C4C(O)=C2)[C@@H]1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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