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ProductsBack/Bisindolylmaleimide IV [Ro 31-6233] [119139-23-0]
Chemical Structure
Chemical Structure
Chemical Structure

Bisindolylmaleimide IV [Ro 31-6233] [119139-23-0]

Research Use Only
AG-CR1-0152
AdipoGen Life Sciences
CAS Number119139-23-0
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight327.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Bisindolylmaleimide IV [Ro 31-6233]
  • Delivery Days Customer
    10
  • CAS Number
    119139-23-0
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C20H13N3O2
  • Molecular Weight
    327.3
  • Scientific Description
    Cell permeable protein kinase C (PKC) inhibitor [1-3]. Inhibits also protein kinase A (PKA) [1,2]. - Chemical. CAS: 119139-23-0. Formula: C20H13N3O2. MW: 327.3. Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
  • SMILES
    O=C1NC(=O)C(C2=CNC3=C2C=CC=C3)=C1C1=CNC2=C1C=CC=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    51202000

References

  • The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
  • Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992)
  • Muscarinic interactions of bisindolylmaleimide analogues: S. Lazareno, et al.; Eur. J. Pharmacol. 360, 281 (1998)