Bisindolylmaleimide VIII . AcOH [Ro 31-7549]

AdipoGen Life Sciences

Bisindolylmaleimide VIII . AcOH [Ro 31-7549]

10

138516-31-1

Research Use Only

>98%

C24H22N4O2 . CH3COOH

398.5 . 60.1

Chemical. CAS: 138516-31-1. Formula: C24H22N4O2 . CH3COOH. MW: 398.5 . 60.1. Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). - Selective protein kinase C (PKC) inhibitor [1-3]. Inhibits proliferation of cultured mouse epidermal keratinocytes [4]. Enhances Fas- and TRAIL-mediated apoptosis [5, 6]. Inhibits T cell-mediated autoimmune diseases [5]. Inhibits stimulation of insulin secretion by glucose [8]. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2) [7].

CC(O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCN)C2=C1C=CC=C2

-20°C,2°C to 8°C

51202000