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Chemical Structure
Bisindolylmaleimide VIII . AcOH [Ro 31-7549] [138516-31-1]
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AG-CR1-0114
CAS Number138516-31-1
Product group Chemicals
Estimated Purity>98%
Molecular Weight398.5 . 60.1
Overview
- SupplierAdipoGen Life Sciences
- Product NameBisindolylmaleimide VIII . AcOH [Ro 31-7549]
- Delivery Days Customer10
- CAS Number138516-31-1
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC24H22N4O2 . CH3COOH
- Molecular Weight398.5 . 60.1
- Scientific DescriptionChemical. CAS: 138516-31-1. Formula: C24H22N4O2 . CH3COOH. MW: 398.5 . 60.1. Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). - Selective protein kinase C (PKC) inhibitor [1-3]. Inhibits proliferation of cultured mouse epidermal keratinocytes [4]. Enhances Fas- and TRAIL-mediated apoptosis [5, 6]. Inhibits T cell-mediated autoimmune diseases [5]. Inhibits stimulation of insulin secretion by glucose [8]. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2) [7].
- SMILESCC(O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCN)C2=C1C=CC=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC51202000