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WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.
WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.
WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.

BMAL1 antibody

GTX50643
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBMAL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    BMAL1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID406
  • Target name
    BMAL1
  • Target description
    basic helix-loop-helix ARNT like 1
  • Target synonyms
    ARNTL, ARNTL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5, basic helix-loop-helix ARNT-like protein 1, ARNT-like protein 1, brain and muscle, PAS domain containing 3, PAS domain-containing protein 3, aryl hydrocarbon receptor nuclear translocator like, aryl hydrocarbon receptor nuclear translocator-like protein 1, bHLH-PAS protein JAP3, basic helix-loop-helix family member e5, basic-helix-loop-helix-PAS orphan MOP3, basic-helix-loop-helix-PAS protein MOP3, brain and muscle ARNT-like 1, class E basic helix-loop-helix protein 5, member of PAS protein 3, member of PAS superfamily 3, mutant basic helix-loop-helix ARNT-like protein 1, testis tissue sperm-binding protein Li 50e
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00327
  • Protein Name
    Basic helix-loop-helix ARNT-like protein 1
  • Scientific Description
    The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hou J, Shen Q, Wan X, et al. REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. Behav Brain Res. 2019,364:167-176. doi: 10.1016/j.bbr.2019.01.038
    Read this paper
  • Hardman JA, Haslam IS, Farjo N, et al. Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle. PLoS One. 2015,10(3):e0121878. doi: 10.1371/journal.pone.0121878
    Read this paper