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WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.
WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.
WB analysis of extracts from HL-60, THP-1, 3T3, HepG2, and MCF-7 cells using GTX50643 BMAL1 antibody.

BMAL1 antibody

GTX50643
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARNTL
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Overview

  • Supplier
    GeneTex
  • Product Name
    BMAL1 antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID406
  • Target name
    ARNTL
  • Target description
    aryl hydrocarbon receptor nuclear translocator like
  • Target synonyms
    ARNT-like protein 1, brain and muscle; aryl hydrocarbon receptor nuclear translocator-like protein 1; basic helix-loop-helix family member e5; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; bHLHe5; bHLH-PAS protein JAP3; BMAL1; BMAL1c; brain and muscle ARNT-like 1; class E basic helix-loop-helix protein 5; JAP3; member of PAS protein 3; member of PAS superfamily 3; MOP3; PAS domain containing 3; PAS domain-containing protein 3; PASD3; testis tissue sperm-binding protein Li 50e; TIC
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00327
  • Protein Name
    Aryl hydrocarbon receptor nuclear translocator-like protein 1
  • Scientific Description
    The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. Hou J et al., 2019 May 17, Behav Brain Res
    Read more
  • Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle. Hardman JA et al., 2015, PLoS One
    Read more