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ProductsBack/c-Met antibody [C3], C-term

c-Met antibody [C3], C-term

GTX100637
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetMET
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Overview

  • Supplier
    GeneTex
  • Product Name
    c-Met antibody [C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.95 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4233
  • Target name
    MET
  • Target description
    MET proto-oncogene, receptor tyrosine kinase
  • Target synonyms
    AUTS9; c-Met; DFNB97; hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; HGFR; proto-oncogene c-Met; RCCP2; scatter factor receptor; SF receptor; tyrosine-protein kinase Met
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08581
  • Protein Name
    Hepatocyte growth factor receptor
  • Scientific Description
    The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 Melanoma Cells Correlates with the Downregulation of Specific Onco-Proteins. De Tomi E et al., 2022 Jan 31, Int J Mol Sci
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  • Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. Pang HH et al., 2019 Apr 25, Nanoscale
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  • Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway. Chen ST et al., 2018 Nov, Oncogene
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  • TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. Pei YF et al., 2018 Jan, Biochim Biophys Acta Mol Basis Dis
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  • Loss of cell invasiveness through PKC-mediated syndecan-1 downregulation in melanoma cells under anchorage independency. Wang C et al., 2014 Nov, Exp Dermatol
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  • C1GALT1 enhances proliferation of hepatocellular carcinoma cells via modulating MET glycosylation and dimerization. Wu YM et al., 2013 Sep 1, Cancer Res
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  • Translocation of Helicobacter pylori CagA into Human B lymphocytes, the origin of mucosa-associated lymphoid tissue lymphoma. Lin WC et al., 2010 Jul 15, Cancer Res
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