C3 / C3a antibody

GeneTex

C3a antibody

9

Binds to a stong band at about 97KDa (C3a), two weaker bands with one at about 115KDa (C3 alpha) and the other at 36-50KDa.

This product can be used at 1:2,000 to 1:10,000 for both ELISA and immunoblot testing. User needs to try out the titrations for optimization in assay.

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

C3

complement C3

acylation-stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3b; complement C3; complement component 3; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; prepro-C3

Chicken

IgY

Complement C3

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Human

2°C to 8°C

12352203