C3 / C3c antibody (FITC)
GTX73472
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Feline, Guinea Pig, Goat, Human, Mink, Mouse, Porcine, Rat, Sheep
TargetC3
Overview
- SupplierGeneTex
- Product NameC3c antibody (FITC)
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with human C3c complement and with the C3c part of C3 and C3b.
- Application Supplier NoteIHC-P: 1:75-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID718
- Target nameC3
- Target descriptioncomplement C3
- Target synonymsacylation-stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3b; complement C3; complement component 3; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; prepro-C3
- HostRabbit
- IsotypeIgG
- Protein IDP01024
- Protein NameComplement C3
- Scientific DescriptionComplement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
- ReactivityBovine, Canine, Feline, Guinea Pig, Goat, Human, Mink, Mouse, Porcine, Rat, Sheep
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b. Park SY et al., 2008 Nov 1, J ImmunolRead more