Bio-Connect

C3 / C3c antibody (FITC)

GTX73472
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Feline, Guinea Pig, Goat, Human, Mink, Mouse, Porcine, Rat, Sheep
TargetC3
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Overview

  • Supplier
    GeneTex
  • Product Name
    C3c antibody (FITC)
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody reacts with human C3c complement and with the C3c part of C3 and C3b.
  • Application Supplier Note
    IHC-P: 1:75-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID718
  • Target name
    C3
  • Target description
    complement C3
  • Target synonyms
    acylation-stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3b; complement C3; complement component 3; complement component C3a; complement component C3b; CPAMD1; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; prepro-C3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01024
  • Protein Name
    Complement C3
  • Scientific Description
    Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
  • Reactivity
    Bovine, Canine, Feline, Guinea Pig, Goat, Human, Mink, Mouse, Porcine, Rat, Sheep
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b. Park SY et al., 2008 Nov 1, J Immunol
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