C3 antibody
GTX72994
ApplicationsFlow Cytometry, ImmunoElectrophoresis, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityEquine, Guinea Pig, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat
TargetC3
Overview
- SupplierGeneTex
- Product NameC3 antibody
- Delivery Days Customer9
- Application Supplier NoteFor FACS: 1/100. For ICC: 1/500 For Ie: Use at an assay dependent dilution. For WB: 1/1000. Optimal dilutions/concentrations should be determined by the researcher.
- ApplicationsFlow Cytometry, ImmunoElectrophoresis, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID718
- Target nameC3
- Target descriptioncomplement C3
- Target synonymsAHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a anaphylatoxin, acylation-stimulating protein cleavage product, complement component 3, complement component C3a, complement component C3b, epididymis secretory sperm binding protein Li 62p, prepro-C3
- HostGoat
- IsotypeIgG
- Protein IDP01024
- Protein NameComplement C3
- Scientific DescriptionComplement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
- ReactivityEquine, Guinea Pig, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kohn M, Lanfermann C, Laudeley R, et al. Complement and Chlamydia psittaci: Non-Myeloid-Derived C3 Predominantly Induces Protective Adaptive Immune Responses in Mouse Lung Infection. Front Immunol. 2021,12:626627. doi: 10.3389/fimmu.2021.626627Read this paper
- Lee HK, Kim HS, Pyo M, et al. Phorbol ester activates human mesenchymal stem cells to inhibit B cells and ameliorate lupus symptoms in MRL.Fas(lpr) mice. Theranostics. 2020,10(22):10186-10199. doi: 10.7150/thno.46835Read this paper
- Johswich KO, McCaw SE, Islam E, et al. In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa. PLoS Pathog. 2013,9(7):e1003509. doi: 10.1371/journal.ppat.1003509Read this paper




