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ProductsBack/C3 antibody

C3 antibody

GTX72994
GeneTex
ApplicationsFlow Cytometry, ImmunoElectrophoresis, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityEquine, Guinea Pig, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat
TargetC3
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Overview

  • Supplier
    GeneTex
  • Product Name
    C3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    For FACS: 1/100. For ICC: 1/500 For Ie: Use at an assay dependent dilution. For WB: 1/1000. Optimal dilutions/concentrations should be determined by the researcher.
  • Applications
    Flow Cytometry, ImmunoElectrophoresis, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID718
  • Target name
    C3
  • Target description
    complement C3
  • Target synonyms
    AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a anaphylatoxin, acylation-stimulating protein cleavage product, complement component 3, complement component C3a, complement component C3b, epididymis secretory sperm binding protein Li 62p, prepro-C3
  • Host
    Goat
  • Isotype
    IgG
  • Protein IDP01024
  • Protein Name
    Complement C3
  • Scientific Description
    Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
  • Reactivity
    Equine, Guinea Pig, Hamster, Human, Mouse, Porcine, Primate, Rabbit, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Kohn M, Lanfermann C, Laudeley R, et al. Complement and Chlamydia psittaci: Non-Myeloid-Derived C3 Predominantly Induces Protective Adaptive Immune Responses in Mouse Lung Infection. Front Immunol. 2021,12:626627. doi: 10.3389/fimmu.2021.626627
    Read this paper
  • Lee HK, Kim HS, Pyo M, et al. Phorbol ester activates human mesenchymal stem cells to inhibit B cells and ameliorate lupus symptoms in MRL.Fas(lpr) mice. Theranostics. 2020,10(22):10186-10199. doi: 10.7150/thno.46835
    Read this paper
  • Johswich KO, McCaw SE, Islam E, et al. In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa. PLoS Pathog. 2013,9(7):e1003509. doi: 10.1371/journal.ppat.1003509
    Read this paper

Datasheet

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