Cardiac Troponin I antibody [8E10]

GeneTex

Cardiac Troponin I antibody [8E10]

9

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation

Research Use Only

Monoclonal

Unconjugated

TNNI3

troponin I3, cardiac type

CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI, troponin I, cardiac muscle, cardiomyopathy, dilated 2A (autosomal recessive), troponin I type 3 (cardiac)

Mouse

IgG1

Troponin I, cardiac muscle

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Bovine, Canine, Feline, Goat, Human, Porcine, Rabbit

2°C to 8°C

12352203