IHC-P analysis of human breast tissue using GTX86900 Caspase 3 (cleaved Asp175) antibody.
IHC-P analysis of human breast tissue using GTX86900 Caspase 3 (cleaved Asp175) antibody.
Caspase 3 (cleaved Asp175) antibody
GTX86900
Overview
- SupplierGeneTex
- Product NameCaspase 3 (cleaved Asp175) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500~1:1000. IHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID836
- Target nameCASP3
- Target descriptioncaspase 3
- Target synonymsapopain; CASP-3; caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; caspase-3; CPP32; CPP-32; CPP32B; cysteine protease CPP32; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1
- Protein IDP42574
- Protein NameCaspase-3
- Scientific DescriptionThe protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimers disease. [provided by RefSeq, Aug 2017]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathway. Zhang MH et al., 2022 Apr, BioengineeredRead more
- Silencing of the lncRNA H19 enhances sensitivity to X-ray and carbon-ions through the miR-130a-3p /WNK3 signaling axis in NSCLC cells. Zhao X et al., 2021 Dec 4, Cancer Cell IntRead more